Kansas Water Science Center
Publications
Highlights
Determination of Atrazine and Atrazine Mercapturate in Drinking Water Samples and in Urine Using Immunoaffinity Solid-Phase Extraction with Positive Ion Spray HPLC/MSBy E.M. Thurman and Chad BastianThe effect of pesticides and their metabolites on man is an important environmental chemistry issue. One method of assessing the amount of pesticide that affects food supplies and drinking water is the measurement of pesticides and metabolites in tap water and in human urine. Because atrazine is present in drinking water of the central United States, it would be informative to be able to measure atrazine metabolites in human urine. An example is the metabolite, atrazine mercapturate. It is an ionic compound that is difficult to isolate and analyze by conventional liquid extraction, solid-phase extraction, and gas chromatography/mass spectrometry. A new analytical method has been developed that uses an immunoaffinity or C-18 solid-phase extraction cartridge to isolate both atrazine and atrazine mercapturate. The solid-phase extraction removes the difficult matrix of tap water and urine samples and concentrates both analytes for HPLC/MS analysis by positive ion spray with a sensitivity in the sub-microgram-per-liter range. Atrazine mercapturate will be discussed in the framework of the flush of herbicides that frequently occurs in tap water during the spring in the Corn Belt in the Central United States. Additional information about the Organic Geochemistry Research Laboratory can be found at: http://ks.water.usgs.gov/studies/reslab/Thurman, E.M., and Bastian, Chad, Determination of atrazine and atrazine mercapturate in drinking water samples and in urine using immunoaffinity solid-phase extraction with positive ion spray HPLC/MS [not presented]: 15th Symposium on Liquid Chromatography/Mass Spectrometry, Montreux, Switzerland, November 9-10, 1998. |
U.S. Department of the Interior |
U.S. Geological Survey
URL: /pubs/abstracts/emt.11-98.html
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The USGS has collected hydrologic information in Kansas since 1895 with the first USGS Cooperative
Water Program funding agreement for 6 streamflow gages with the Kansas Water Board. USGS collects streamflow
and gage-height data; reservoir content; water-quality and water-quantity data; suspended-sediment data;
and groundwater levels. Hydrologic studies are conducted on national, regional, statewide, and local levels.
The USGS in Kansas works cooperatively with 31 Federal, State, and local agencies, such as the Kansas Water Office, the U.S.Army Corps of Engineers, and the City of Wichita